ANTIMETABOLITES OF SEROTONIN
نویسندگان
چکیده
منابع مشابه
Differentiation between receptors for serotonin and tryptamine by means of the exquisite specificity of antimetabolites.
I. Effects of Reserpine and Hydralazine on Carotid and Splanchnic Nerve Activity and Blood Pressure. A. S. Dontas 1 II. Action and Metabolism of Chiorpromazine Sulfoxide in Man. John C. Davidson, Luther L. Terry and Albert Sjoerdsma 8 III. Differentiation Between Receptors for Serotonin and Tryptamine by Means of the Exquisite Specificity of Antimetabolites. D. W. Woolley andE.Shaw 13 IV. A Qua...
متن کاملA Study of Antimetabolites
Pettus gave everything he had as a medical missionary in China and Dr. Edward H. Hume has drawn a clear and sympathetic picture of this man, his aspirations, and those qualities which distinguished him as a medical scientist at home and abroad. On 23 November 1945 was received the melancholy cablegram from Huangping, China, which read as follows: "Dr. Pettus killed in airplane accident at Huang...
متن کاملStudies of Antimetabolites* Ii. I-acetylpyridine
When 3acetylpyridine (3-AP) is fed to dogs, large amounts of a normal end-product of nicotinic acid metabolism, N’-methylnicotinamide (NMeN), appear in the urine (1). This finding might be interpreted as evidence that 3-AP, acting as an antivitamin, displaces nicotinamide from its nucleotides or prevents its incorporation therein, or, alternatively, that 3-AP is biologically oxidized to nicotin...
متن کاملStudies of antimetabolites. II. 3-Acetylpyridine.
When 3acetylpyridine (3-AP) is fed to dogs, large amounts of a normal end-product of nicotinic acid metabolism, N’-methylnicotinamide (NMeN), appear in the urine (1). This finding might be interpreted as evidence that 3-AP, acting as an antivitamin, displaces nicotinamide from its nucleotides or prevents its incorporation therein, or, alternatively, that 3-AP is biologically oxidized to nicotin...
متن کاملProblems in the Designing of Antimetabolites †
Historically, the most useful medicinal agents have been obtained by empirical screening or by the chemical modification of compounds of known activity in the hope of making them more effective. To these approaches a new one was added in recent years-antimetabolites. An antimetabolite may be defined as a compound bearing structural resemblance to a metabolite and capable of being attached to th...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1953
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)52615-1